VigiLanz patient monitoring software helps physicians and pharmacists identify and prevent adverse drug events

Products - DPV

The Dynamic PharmacoVigilance® Module (DPV)

Identify, Anticipate and Prevent Adverse Drug Events (ADE)


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Listen to comments from VigiLanz user John Russillo, RPh, manager of clinical pharmacy services in the Hospital Operations Division of the John Muir Health System. Russillo talks about the increased pressure on health care delivery performance and drug safety as being paramount. Today there is also greater emphasis on reporting and reducing adverse spend. He outlines what problems he was trying to solve when evaluating adverse drug system.

In a world of greater and growing medication complexity, pharmacy professionals are being asked to do more monitoring and re-checking to identify patients that may be suffering adverse events from their medications, but without the necessary tools to do so productively. The Dynamic PharmacoVigilance® Module (DPV) automates the monitoring of drug therapy and its effect on patient physiology, as well as the changes of patient physiology and the resultant impact on drug therapy. It identifies preventable adverse drug events in real-time and provides the clinician with actionable data and guidance.

Taking medication safety to the next level

Some of the more prevalent medication safety technologies under consideration at hospitals today are CPOE and bedside bar coding. CPOE is intended to prevent medication errors only at the point in time when the order is entered. Bedside Bar Coding is designed to prevent medication errors only at the time the drug is administered. The Dynamic PharmacoVigilance® Module (DPV) complements both of these strategies, taking prevention a step further by identifying and preventing ADEs in real time after the drug has been ordered and administered, 24/7. Based on the clinical guidelines in its rules it warns that an appropriate course of action should be taken and monitors the event to ensure that the action is taken.

The best news is that DPV provides this real-time surveillance at a fraction of the cost of these other technologies.

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How DPV works

DPV is a comprehensive support solution offering Real-Time, a proprietary feature that combines lab test and pharmacy electronic data in real time, automatically and seamlessly. It supports the pharmacists’ and clinicians’ efforts in addressing a broad range of frequent, as well as uncommon, ADEs. DPV does this through the use of both simple and very complex ADE rule sets contained in the Hospital ADE Rule Library of over 1,000 rules. These rules are identified and selected with Easy Select™, a simple method of defining and selecting ADE rules. A clinician can customize an existing rule or build a completely custom rule in just a few minutes without requiring any IT support.

The DPV module also uses Forward Seek™, a forward-looking feature that looks for planned changes in the patient’s medication orders that would satisfy a rule. Conversely, Forward Seek™ also looks for changes in the patient’s drug regime that would result in a warning notification or alert. During this process the DPV module automatically analyzes the patient’s data without requiring manual data entry through the use of a transparent feature called Survail™, a proprietary surveillance search engine technology that operates 24/7 with ADE rules. Best of all, the DPV module incorporates the use of a dynamic interval that automatically adjusts the Good Medical Practice Interval of an ADE rule to reflect the criticality of the lab and the potential dangers of a deteriorating lab trend. If the medical practice interval expires without the clinically appropriate action taken by the clinician, then an alert notification will be made. Both warnings and alert notifications can be issued to the appropriate personnel via email, pager or PDA based on guidance of the rule enabling the pharmacy and clinical staff to respond proactively. And all activations of all patients can be viewed and addressed at all times using only a browser, from any web enabled computer in the hospital, using your secure access code.

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VigiLanz user John Russillo, RPh, manager of clinical pharmacy services in the Hospital Operations Division at thhe John Muir Health System, discusses the usefulness of altering rules within the system. For example, Russillo was able to change the threshold alert value to avoid repetitive false positives. It's a unique aspect of the VigiLanz system for customizing according to their patient needs.

See Example Rules

Real-World technology for real-time practice

The Dynamic PharmacoVigilance® Module (DPV) was conceived and developed by practicing clinicians with decades of combined experience. It was designed with an open architecture and works with any hospital system. Easy Select™ makes it fast and easy to add rules to the Rule Library, edit rule definitions or adapt a rule function for a specific need. Sets of rules can quickly be customized using filters such as age, gender, weight, doctor and unit.

The solution to preventing ADEs is here

Treatment complexity, accelerated drug introductions, and resource constraints have all impacted the quality of care. Health care providers are looking for solutions that bring valuable, real-time information to the treatment pathway, information that can be acted upon before an adverse drug event occurs --- not just after statistical reports are assembled.

Health care teams want and need more information with less busy work and more time to perform their clinical tasks-where they belong. The solution to the problem of ADEs is here today: Dynamic PharmacoVigilance®